Mind you, I'm not suggesting people drink and if you do, it is of your own free will. Some people will find a way to drink, so here's to you.
Every time Frank says, "No doubt about it", take a drink. Every time Frank says, "Definitely", take a drink. Every time Frank something to the effect of, "I was just about to say that", take a drink.
Following just the first line, you will be lucky if you don't succumb to alcohol poisoning.
Anyone under 21, please do not drink alcohol. Substitute with a carbonated beverage of your choice. By the end of the game, you will feel like you are about to explode.
Anybody who only drinks occasionally, do not drink anything more powerful than domestic U.S. beer. This should still bring the desired effect of the porcelain gods beckoning you to their will.
Anybody who can be classified as a certified drunk, feel free to indulge in the hard stuff. With your reputation, you'll get there anyway. Why not make a game out of it?
This is definitely (if I were Frank, you'd have already swigged one back) not an endorsement to drink or get drunk. It's just another variation of the "Hi, Bob" game.